The five C’s of positive youth development (PYD) (competence, confidence, character,
caring, and connection) have been associated with adaptive development among young
people. Gender differences in young people’s wellbeing and mental health have been
studied and analyzed, but the investigation into their association with the five C’s is still in
its infancy. In the present study, we analyzed the influence of the five C’s on the wellbeing,
more specifically, anxiety, social alienation, general wellbeing, physical symptoms, and
psychological symptoms, of Portuguese adolescents, by gender. Participants were 5th–
12th grade students attending public schools in Lisbon, Portugal. The questionnaire was
administered to 384 adolescents. The results indicated important gender differences in
young people’s wellbeing. The results revealed some differences between genders that
should be considered in interventions that aim to promote the wellbeing of adolescents.
On the other hand, confidence was positively associated with mental health and
wellbeing for both boys and girls, skill should be promoted among young people,
because it was competence that revealed the greatest association with wellbeing,
among the variables analyzed.