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dc.contributor.authorDacosta Sánchez, Daniel 
dc.contributor.authorGonzález Ponce, Bella M.
dc.contributor.authorFernández Calderón, Fermín 
dc.contributor.authorLozano Rojas, Óscar Martín
dc.identifier.citationDacosta Sánchez, D., González Ponce, B. M., Fernández Calderón, F. ... Lozano Rojas, O. M. (2021). Profiles of patients with cocaine and alcohol use disorder based on cognitive domains and their relationship with relapse. Drug and Alcohol Dependence, 218, 108349. DOI:
dc.description.abstractBackground: Relapse in drug use constitutes a research topic on addiction that is relevant for understanding both the addictive process and its clinical implications. The objective of this study was to explore if it is possible to identify patient profiles according to their performance on cognitive tasks whilst examining the relationship between such profiles and relapse. Methods: The sample consisted of 222 patients with dependence on cocaine and / or alcohol, of which 86% were men. Cognitive domains related to salience, decision- making, and emotional processing were measured. Results: Latent class analysis revealed three patient profiles that differ in terms of performance on cognitive tasks. Two of these profiles are clearly differentiated in terms of their execution of the impulsive decision-making task. The third patient profile, unlike the latter two, is composed of patients with severe alterations in the three domains evaluated. Analysis revealed that patients in Profile 3 are those with the highest rates of relapse in cocaine (Profile 1 = 40.3%; Profile 2 = 35.6%; Profile 3 = 69.2%; Chi2 = 9.169; p <.05) and cocaine and alcohol use (Profile 1 = 55.1%; Profile 2 = 54.1%; Profile 3 = 80%; Chi2 = 6.698; p <.05). Conclusions: The results support the postulates of the I-RISA model. From a clinical perspective, these findings highlight the need for a comprehensive evaluation of the cognitive domains involved in addiction.es_ES
dc.rightsAtribución-NoComercial-SinDerivadas 3.0 España*
dc.subject.otherCocaine and alcohol relapsees_ES
dc.subject.otherEmotional processinges_ES
dc.subject.otherIncentive saliencees_ES
dc.subject.otherLatent profilees_ES
dc.titleProfiles of Patients with Cocaine and Alcohol use Disorder Based on Cognitive Domains and Their Relationship with Relapsees_ES

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