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Browsing by Author "Basílio, Nuno"
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Drug delivery by controlling a supramolecular host–guest assembly with a reversible photoswitch
Basílio, Nuno; Pischel, Uwe(Wiley, 2016)
The reversibly switchable trans‐chalcone/flavylium photochromic system was successfully coupled to the complexation equilibrium of a drug‐cucurbit[7]uril host–guest assembly. Hence, the phototriggered release of memantine ... -
Photomodulation of ultrastable host–guest complexes in water and their application in light-controlled steroid release
Máximo, Patrícia; Colaço, Miriam; Pauleta, Sofia R.; Costa, Paulo J.; Pischel, Uwe; Parola, A. Jorge; Basílio, Nuno (Royal Society of Chemistry, 2022)
The cucurbit[8]uril (CB8) synthetic receptor is shown to form high-affinity host–guest complexes with dicationic dithienylethene (DTE) photoswitches in water. ITC experiments combined with computational studies suggest ... -
Toward Light-Controlled Supramolecular Peptide Dimerization
Fernandes, Rita J.; Remón Ruiz, Patricia; Moro, Artur J.; Seco, André; Ferreira, Ana S. D.; Pischel, Uwe; Basílio, Nuno (American Chemical Society, 2021-06-01)
The selective photodeprotection of the NVoc-modified FGG tripeptide yields the transformation of its 1:1 receptor−ligand complex with cucurbit[8]uril into a homoternary FGG2@CB8 assembly. The resulting lightinduced ...