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Browsing by Author "Pischel, Uwe"
Now showing items 1-20 of 21
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Arylisoquinoline-derived organoboron dyes with a triaryl skeleton show dual fluorescence
Fernandes Pais, Vania Cristina
; Neumann, Tristan; Vayá, Ignacio; Jiménez Molero, María Consuelo; Ros, Abel; Pischel, Uwe (Beilstein-Institut, 2019)
Four new dyes that derive from borylated arylisoquinolines were prepared, containing a third aryl residue (naphthyl, 4-methoxynaphthyl, pyrenyl or anthryl) that is linked via an additional stereogenic axis. The triaryl ... -
BASHY Dye Platform Enables the Fluorescence Bioimaging of Myelin Debris Phagocytosis by Microglia during Demyelination
Pinto, Maria V.; Santos, Fabio; Barros, Catarina; Ribeiro, Ana Rita; Pischel, Uwe; Gois, Pedro; Fernandes, Adelaide (MDPI, 2021)
Multiple sclerosis (MS) is a demyelinating disease of the central nervous system that is characterized by the presence of demyelinated regions with accumulated myelin lipid debris. Importantly, to allow effective ... -
Bis-borylated arylisoquinoline-derived dyes with a central aromatic core: towards efficient fluorescent singlet-oxygen photosensitizers
Campos González, René; Vázquez Domínguez, Pablo; Remón Ruiz, Patricia; Nájera, Francisco; Collado, Daniel; Pérez Inestrosa, Ezequiel; Boscá Mayans, Francisco; Ros, Abel; Pischel, Uwe (Royal Society of Chemistry, 2022)
Conveniently modified polycyclic aromatic hydrocarbon (PAH) fluorophores are obtained by a bromination–borylation sequence. The bis-borylated dyes show red-shifted absorption (λabs,max > 450 nm) and emission (λf,max > 500 ... -
Design and characterization of molecular fluorescent architectures for potential applications as sensors and logic switches
Fernandes Pais, Vania Cristina (Universidad de Huelva, 2014)
The increasing complexity of information technology and the therewith connected demands for miniaturization have alimented the need for alternative small-scale approaches to computing and data processing. Molecules can be ... -
Diseño de moléculas con actividad biológica : síntesis e Implicaciones en química supramolecular
(Universidad de Huelva, 2019)Uno de los grandes desafíos dentro de la Química Supramolecular es conseguir imitar el comportamiento de las biomoléculas. Para ello, es necesario el diseño de compuestos sintéticos que tengan gran afinidad y selectividad ... -
Diseño y caracterización de compuestos organoboro fluorescentes y sus aplicaciones funcionales
(Universidad de Huelva, 2020)La presente Memoria de Tesis Doctoral titulada “Diseño y Caracterización de Colorantes Organoboro Fluorescentes y sus Aplicaciones Funcionales” está dirigida hacia el diseño, caracterización fotofísica y aplicación de ... -
Diseño y caracterización de nuevos sistemas fluorescentes para su utilización como interruptores y puertas lógicas moleculares : implicación de procesos de transferencia electrónica y de energía en el estado excitado
(Universidad de Huelva, 2014)La investigación de interruptores moleculares fotoactivos y/o fluorescentes es un campo de la química con intensa actividad en todo el mundo. Esta tesis doctoral contribuye a estas actividades con el diseño y la caracterización ... -
Drug delivery by controlling a supramolecular host–guest assembly with a reversible photoswitch
Basílio, Nuno; Pischel, Uwe (Wiley, 2016)
The reversibly switchable trans‐chalcone/flavylium photochromic system was successfully coupled to the complexation equilibrium of a drug‐cucurbit[7]uril host–guest assembly. Hence, the phototriggered release of memantine ... -
Excited-State Pathways of Four-Coordinate N,C-Chelate Organoboron Dyes
Boscá Mayans, Francisco; Cuquerella Alabort, Maria Consuelo; Fernandes Pais, Vania Cristina; Ros Lao, Abel; Pischel, Uwe (Wiley-Blackwell, 2017-12)
The excited-state behavior of four-coordinate N,C-chelate organoboron dyes, based on arylisoquinoline ligands with varying degree of charge-transfer character, was characterized. Data related to excited triplet state ... -
Five-Component Self-Assembly of Cucurbituril-Based Hetero-pseudorotaxanes
Parente Caldeira Carvahlo, Cátia Diana; Domínguez Hidalgo, Zoe; Domínguez Linares, Cristina; El- Sheshtawy, Hamdy S.; Da Silva, José Paulo; Fernández Arteaga, Jesús; Pischel, Uwe (Wiley Open Access, 2017)
[5]Pseudorotaxanes can be obtained by self-sorting using heteroditopic guests and various cucurbituril homologues as hosts. The assembly and chemically induced disassembly of the pseudorotaxanes can be monitored by measuring ... -
Highly Efficient Energy Transfer Cassettes by Assembly of Boronic Acid Derived Salicylidenehydrazone Complexes
Santos, Fabio; Domínguez, Zoe; Alcaide, María M.; Matos, Ana; Florindo, Helena; Candeias, Nuno; Gois, Pedro; Pischel, Uwe (Wiley-Blackwell, 2018-09)
Energy transfer cassettes that build on the platform of boronic acid derived salicylidenehydrazone (BASHY) complexes were prepared. The functional flexibility of the BASHY chromophore was underpinned by its tunable role ... -
Molecular switches as platforms for Information processing
Pischel, Uwe (Schweizerische Chemische Gesellschaft, 2014)
This article shows how to teach molecules the basics of logic and how to integrate complicated logic operations with relatively simple molecules. A special focus is put on the realization of multi-level fluorescent switches ... -
Photomodulation of ultrastable host–guest complexes in water and their application in light-controlled steroid release
Máximo, Patrícia; Colaço, Miriam; Pauleta, Sofia R.; Costa, Paulo J.; Pischel, Uwe; Parola, A. Jorge; Basílio, Nuno (Royal Society of Chemistry, 2022)
The cucurbit[8]uril (CB8) synthetic receptor is shown to form high-affinity host–guest complexes with dicationic dithienylethene (DTE) photoswitches in water. ITC experiments combined with computational studies suggest ... -
Phototriggered release of amine from a cucurbituril macrocycle
Vázquez Piqué, Javier; Romero, M.A.; Dsouza, R. N.; Pischel, Uwe (Royal Society of Chemistry, 2016)
A method for the phototriggered release of a biogenic amine from the host–guest complex with the cucurbit[7]uril macrocycle in aqueous solution was devised. The approach exploits a photoinduced pH jump from 8 to 5, combined ... -
Precise supramolecular control of surface coverage densities on polymer micro- and nanoparticles
Zhang, Shuai; Domínguez, Zoe; Khaleel, Assaf; Nilam, Mohamed; Thiele, Thomas; Pischel, Uwe; Schedler, Uwe (Royal Society of Chemistry, 2018-12)
We report herein the controlled surface functionalization of micro- and nanoparticles by supramolecular host–guest interactions. Our idea is to exploit the competition of two high-affinity guests for binding to the ... -
Red-emitting tetracoordinate organoboron chelates : synthesis, photophysical properties, and fluorescence microscopy
Fernandes Pais, Vania Cristina; Ramírez López, Pedro; Romero Arenas, Antonio; Collado, Daniel; Nájera, Francisco; Pérez Inestrosa, Ezequiel; Fernández, Rosario; Lassaletta, José M.; Ros, Abel; Pischel, Uwe (American Chemical Society, 2016)
Seven tetra-coordinate organoboron fluorophores with hetero-biaryl N,O or N,N chelate ligands were prepared and photophysically characterized (in toluene). The electronic variation of the heteroaromatic moiety provided a ... -
Strongly Emissive and Photostable Four‐Coordinate Organoboron N,C Chelates and Their Use in Fluorescence Microscopy
Fernandes Pais, Vania Cristina; Alcaide, María M.; Pischel, Uwe (Wiley, 2015)
Six strongly fluorescent four-coordinate organoboron N,C chelates containing an aryl isoquinoline skeleton were prepared. Remarkably, the fluorescence quantum yields reach values of up to 0.74 in oxygen-free toluene. The ... -
Supramolecular cucurbituril complexes for applications in bio-relevant contexts
(Universidad de Huelva, 2015)In the last decade, macrocyclic hosts have been used as an exciting new tool in functional supramolecular chemistry applications ranging from sensing, via drug delivery to catalysis and materials chemistry. This doctoral ... -
Toward Light-Controlled Supramolecular Peptide Dimerization
Fernandes, Rita J.; Remón Ruiz, Patricia; Moro, Artur J.; Seco, André; Ferreira, Ana S. D.; Pischel, Uwe; Basílio, Nuno (American Chemical Society, 2021-06-01)
The selective photodeprotection of the NVoc-modified FGG tripeptide yields the transformation of its 1:1 receptor−ligand complex with cucurbit[8]uril into a homoternary FGG2@CB8 assembly. The resulting lightinduced ... -
Toward Two-Photon Absorbing Dyes with Unusually Potentiated Nonlinear Fluorescence Response
Benítez Martín, Carlos; Li, Shiming; Domínguez Alfaro, Antonio; Pischel, Uwe (American Chemical Society, 2020-08)
The combination of two two-photon-induced processes in a Förster resonance energy transfer (FRET)-operated photochromic fluorene-dithienylethene dyad lays the foundation for the observation of a quartic dependence of the ...
