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Browsing by Author "Pérez Romero, Pedro José"
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A competing, dual mechanism for catalytic direct benzene hydroxylation from combined experimental-DFT studies
Vilella, Laia; Conde Alcántara, Ana Isabel; Ballcells, David; Díaz Requejo, María Mar
; Lledós, Agustín; Pérez Romero, Pedro José (Royal Society of Chemistry, 2017)
A dual mechanism for direct benzene catalytic hydroxylation is described. Experimental studies and DFT calculations have provided a mechanistic explanation for the acid-free, TpxCu-catalyzed hydroxylation of benzene with ... -
A Quantitative Model for Alkane Nucleophilicity Based on C−H Bond Structural/Topological Descriptors
Besora, María; Olmos Verge, Andrea; Noverges, Bárbara; Asensio, Gregorio; Caballero Bevia, Ana; Maseras, Feliu; Pérez Romero, Pedro José (Wiley, 2020)
A first quantitative model for calculating the nucleophilicity of alkanes is described. A statistical treatment was applied to the analysis of the reactivity of 29 different alkane C−H bonds towards in situ generated metal ... -
Aerobic Intramolecular Carbon-Hydrogen Bond Oxidation Promoted by Cu(I) Complexes
Álvarez, María; Molina, Francisco; Romero Fructos-Vázquez, Manuel; Urbano Baena, Juan; Álvarez, Eleuterio; Sodupe, Mariona; Lledós, Agustí; Pérez Romero, Pedro José (Royal Society of Chemistry, 2020-09)
The oxidation of C–H bonds by copper centres in enzymes with molecular oxygen takes place in nature under ambient conditions. Herein we report a similar transformation in which under ambient pressure and temperature (1 ... -
Alkenylboronates : synthesis and applications
Carreras, Javier; Caballero Bevia, Ana; Pérez Romero, Pedro José (Wiley, 2019)
Organoboron compounds have become one of the most versatile building blocks in organic synthesis owing to their accessible and efficient conversion into many different functional groups. In particular, alkenyl boronates ... -
Alkoxydiaminophosphine Ligands as Surrogates of NHCs in Copper Catalysis
Pizarro, Juan Diego; Molina, Francisco; Romero Fructos-Vázquez, Manuel; Pérez Romero, Pedro José (Wiley, 2020-08)
A family of phosphine ligands containing a five‐membered ring similar to the popular N‐heterocyclic carbene ligands and an alkoxy third substituent has been developed. These alkoxydiaminophosphine ligands (ADAP) can be ... -
Atom Transfer Radical Reactions as a Tool for Olefin Functionalization : On the Way to Practical Applications
Muñoz Molina, José María; Rodríguez Belderraín, Tomás; Pérez Romero, Pedro José (Wiley-VCH Verlag, 2011)
Transition-metal-catalyzed atom transfer radical reactions of halogenated compounds with olefins constitute a versatile tool in organic synthesis within the area of C–C bond forming transformations. The inter- or intramolecular ... -
Carbene-Controlled Regioselective Functionalization of Linear Alkanes under Silver Catalysis
Álvarez, María; Molina, Francisco; Pérez Romero, Pedro José (American Chemical Society, 2022)
Control of the regioselectivity in the functionalization of C–H bonds of linear alkanes C2H2n+2 via carbene transfer from diazo compounds is restricted to the use of rhodium-based catalysts, which govern the reaction outcome ... -
Catalytic cyclopropanation of polybutadienes
Urbano Baena, Juan; Korthals, Brigitte; Díaz Requejo, María Mar; Pérez Romero, Pedro José; Mecking, Stefan (Wiley, 2010)
Catalytic cyclopropanation of commercial 1,2- or 1,4- cis -polybutadiene, respectively, with ethyl diazoacetate catalyzed by [Tp Br3 Cu(NCMe)] (Tp Br3 ¼ hydrotris(3,4,5-tribromo-1-pyrazo- lyl)borate) at room ... -
Catalytic Functionalization of C-H Bonds of Azulene by Carbene/Nitrene Incorporation
Carreras, Javier; Popowski, Yanay; Caballero Bevia, Ana; Amir, Elizabeth; Pérez Romero, Pedro José (American Chemical Society, 2018)
The selective catalytic functionalization of the C-H bond of azulene upon incorporation of carbene or nitrene units with metal-based catalysts is described. Ethyl diazoacetate or ArI=NTs are employed as carbene or nitrene ... -
Catalytic Nitrene Transfer To Alkynes: A Novel and Versatile Route for the Synthesis of Sulfinamides and Isothiazoles
Rodríguez, Manuel R.; Beltrán Martín, Álvaro; Mudarra, Ángel L.; Álvarez, Eleuterio; Maseras, Feliu; Díaz Requejo, María Mar; Pérez Romero, Pedro José (Wiley, 2017)
A novel transformation is reported for the reaction of terminal or internal alkynes with the nitrene precursor PhI=NTs (Ts=p-toluenesulfonyl) in the presence of catalytic amounts of Tp(Br3)Cu(NCMe) (Tp(Br3)=hydrotris(3,4 ... -
Coinage metal complexes bearing fluorinated N-Heterocyclic carbene ligands
Delgado Rebollo, Manuela; García Morales, Cristina; Maya, Celia; Prieto Cárdenas, María Auxiliadora; Echavarren, Antonio M.; Pérez Romero, Pedro José (Elsevier, 2019-10)
The synthesis of novel fluorinated symmetrical and unsymmetrical imidazolium salts as well as their corresponding coinage metal complexes is described. The silver derivatives were prepared using Ag2O as the metal source ... -
Complejos de Cu (I) con ligandos de tipo homoescorpionato (Tpx) como catalizadores en reacciones de transferencia de carbenos a diferentes sustratos orgánicos : efecto de los ligandos tpx en la quimio-, regio- y diastereoselectividad de las reacciones
Caballero Bevia, Ana (2004)
Esta tesis doctoral se ha dicidido en tres capítulos. El primero está dedicado a la síntesis y caractrización de nuevos complejos de cobre con ligandos de tipo trispirazolilborato, Tpx , obtenidos mediante la reacción de ... -
Complejos de Cu y Au con ligandos alcoxidiaminofosfinas (ADAP): aplicaciones catalíticas en reacciones de transferencia selectiva de grupos de carbeno
(Universidad de Huelva, 2021)Los estudios que se presentan en esta Tesis Doctoral están basados en la síntesis de nuevos complejos de cobre y oro con ligandos alcoxidiaminofosfinas (ADAP), y el empleo de los mismos como catalizadores en reacciones ... -
Copper(I)-Arene Complexes with a Sterically Hindered Tris(pyrazolyl)borate Ligand
Álvarez, María; Urbano Baena, Juan; Romero Fructos-Vázquez, Manuel; Álvarez, Eleuterio; Pérez Romero, Pedro José (Wiley-VCH Verlag, 2018)
A series of arene copper(I) complexes bearing the hydrotris(3-mesitylpyrazolyl)borate ligand (Tp(Ms)) of general formula Tp(Ms)Cu(arene) (arene = toluene, 1; nitrobenzene, 2; chlorobenzene, 3; and iodobenzene, 4) has been ... -
Copper-catalysed radical reactions of alkenes, alkynes and cyclopropanes with N–F reagents
Muñoz Molina, José María; Rodríguez Belderraín, Tomás; Pérez Romero, Pedro José (Royal Society of Chemistry, 2020-10)
The mild generation of nitrogen-centred radicals from N–F reagents has become a convenient synthetic tool. This methodology provides access to the aminative difunctionalisation of alkenes and alkynes and the radical ... -
Copper-Catalyzed Dehydrogenative Amidation of Light Alkanes
Fuentes Domínguez, María Ángeles; Gava, Riccardo; Saper, Noam I.; Romero, Erik A.; Caballero Bevia, Ana; Hartwig, John F.; Pérez Romero, Pedro José (Wiley, 2021-05)
The functionalization of C-H bonds in light alkanes, particularly to form C-N bonds, remains a challenge. We report the dehydrogenative coupling of amides with C1–C4 hydrocarbons to form N-alkyl amide products with tBuOOtBu ... -
Copper-Catalyzed N-F Bond Activation for Uniform Intramolecular C-H Amination Yielding Pyrrolidines and Piperidines
Bafaluy, Daniel; Muñoz Molina, José María; Funes Ardoiz, Ignacio; Herold, Sebastian; Aguirre, Adiran J. de; Zhang, Hongwei; Maseras, Feliu; Rodríguez Belderraín, Tomás; Pérez Romero, Pedro José; Muñiz, Kilian (Wiley, 2019-06)
The dual function of the N-F bond as an effective oxidant and subsequent nitrogen source in intramolecular aliphatic C-H functionalization reactions is explored. Copper catalysis is demonstrated to exercise full regio- and ... -
Copper-Induced Ammonia N-H Functionalization
Álvarez, María; Álvarez, Eleuterio; Romero Fructos-Vázquez, Manuel; Urbano Baena, Juan; Pérez Romero, Pedro José (Royal Society of Chemistry, 2016)
The activation of ammonia has been achieved with the aid of the TpMsCu core (TpMs = hydrotris(3-mesityl-pyrazolyl)borate). Complexes of the general composition TpMsCu(amine) (1–4) including the ammonia adduct TpMsCu(NH3) ... -
Copper‐Catalyzed Selective Pyrrole Functionalization by Carbene Transfer Reaction
Rodríguez, Anabel M.; Molina, Francisco; Díaz Requejo, María Mar; Pérez Romero, Pedro José (Wiley, 2020-02)
1H‐Pyrroles can be directly functionalized by means of the incorporation of carbene groups from diazo compounds, in a process catalyzed by TpxCu complexes (Tpx=hydrotrispyrazolylborate ligand). The reactions take place ... -
Dimensioning the term carbenoid
Caballero Bevia, Ana; Pérez Romero, Pedro José (Wiley, 2017)
The current use of the term carbenoid is discussed, particularly in the context of carbene transfer reactions from diazo compounds, where intermediates of type LnM=CR1R2, or one of its resonance forms, are tagged which ...
