@article{10272/16959, year = {2019}, month = {9}, url = {http://hdl.handle.net/10272/16959}, abstract = {The food industry has currently shown great interest in alternative sweeteners to sugars with the aim of producing healthier products. In light of this, steviol glycosides are natural low-caloric sweeteners present in Stevia rebaudiana, which have additionally been described as bioactive components with potential therapeutic properties. In this work, a green method for the extraction of steviol glycosides from stevia leaves was optimized by applying a factorial screening design of five variables (time, temperature, agitation, grinding, and sample–solvent ratio) and the subsequent response surface design of Box-Behnken. The optimized extraction method allows for the recovery of stevia sweeteners in a simple and e cient manner by using tap water as the extractant, without the application of an auxiliary energy source to reduce costs, thus representing an interesting strategy for their industrial-scale production.}, publisher = {MDPI}, keywords = {Steviol glycosides}, keywords = {Green extraction}, keywords = {Stevia leaves}, keywords = {Stevioside}, keywords = {Rebaudioside A}, title = {Simple and Efficient Green Extraction of Steviol Glycosides from Stevia rebaudiana Leaves}, doi = {10.3390/foods8090402}, author = {López Carbón, Verónica and Sayago Gómez, Ana and González Domínguez, Raúl and Fernández Recamales, María Ángeles}, }