@article{10272/15969,
year = {2018},
url = {http://hdl.handle.net/10272/15969},
abstract = {A novel, highly enantio- and diastereoselective
synthesis of 1-boryl-2,3-disubstituted cyclopropanes has been
developed by means of the cyclopropanation of alkenylboronates
with ethyl diazoacetate in the presence of catalytic
amounts of a chiral copper(I) complex. The products can also
be directly accessed from alkynes through an operationally
simple, sequential hydroboration–cyclopropanation protocol.
The resulting enantioenriched 1-boryl-2,3-disubstituted cyclopropanes
are versatile synthetic intermediates that undergo
further transformations at the carbon–boron bond.},
organization = {We thank MINECO for financial support (CTQ2014-52769-
C03-01-R and Juan de la Cierva fellow for J.C.) and Junta de
Andaluc a (P12-FQM-1765). We also thank Riccardo Gava
and Cristina Gonzalez for additional experiments and Francisco
Molina for X-ray diffraction studies.},
publisher = {Wiley},
keywords = {Alkenylboronates},
keywords = {Asymmetric catalysis},
keywords = {Cyclopropanes},
keywords = {Copper},
keywords = {Hydroboration},
title = {Enantio‐ and Diastereoselective Cyclopropanation of 1‐Alkenylboronates : Synthesis of 1‐Boryl‐2,3‐Disubstituted Cyclopropanes},
doi = {10.1002/anie.201710415},
author = {Carreras, Javier and Caballero Bevia, Ana and Pérez Romero, Pedro José},
}