dc.contributor.author | Montero Lobato, Zaida | |
dc.contributor.author | Vázquez, María | |
dc.contributor.author | Navarro Domínguez, Francisco Javier | |
dc.contributor.author | Fuentes, Juan Luis | |
dc.contributor.author | Bermejo, Elisabeth | |
dc.contributor.author | Garbayo Nores, Inés | |
dc.contributor.author | Vílchez Lobato, Carlos | |
dc.contributor.author | Cuaresma Franco, María | |
dc.date.accessioned | 2019-03-22T11:34:40Z | |
dc.date.available | 2019-03-22T11:34:40Z | |
dc.date.issued | 2018-11 | |
dc.identifier.citation | Montero-Lobato, Z., Vázquez, M., Navarro, F., Fuentes, J., Bermejo, E., Garbayo, I., … Cuaresma, M. (2018). Chemically-Induced Production of Anti-Inflammatory Molecules in Microalgae. Marine Drugs, 16(12), 478. https://doi.org/10.3390/md16120478 | es_ES |
dc.identifier.issn | 1660-3397 | |
dc.identifier.uri | http://hdl.handle.net/10272/16116 | |
dc.description.abstract | Microalgae have been widely recognized as a valuable source of natural, bioactive molecules
that can benefit human health. Some molecules of commercial value synthesized by the microalgal
metabolism have been proven to display anti-inflammatory activity, including the carotenoids lutein
and astaxanthin, the fatty acids EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid),
and sulphated polysaccharides. These molecules can accumulate to a certain extent in a diversity of
microalgae species. A production process could become commercially feasible if the productivity is
high and the overall production process costs are minimized. The productivity of anti-inflammatory
molecules depends on each algal species and the cultivation conditions, the latter being mostly related
to nutrient starvation and/or extremes of temperature and/or light intensity. Furthermore, novel
bioprocess tools have been reported which might improve the biosynthesis yields and productivity
of those target molecules and reduce production costs simultaneously. Such novel tools include the
use of chemical triggers or enhancers to improve algal growth and/or accumulation of bioactive
molecules, the algal growth in foam and the surfactant-mediated extraction of valuable compounds.
Taken together, the recent findings suggest that the combined use of novel bioprocess strategies
could improve the technical efficiency and commercial feasibility of valuable microalgal bioproducts
production, particularly anti-inflammatory compounds, in large scale processes. | es_ES |
dc.description.sponsorship | Z.M.-L. is beneficial of a predoctoral grant from "Plan Propio de Investigacion" from the University of Huelva (Spain). Part of the scientific information reviewed in this paper (Section 3) was produced within the MIRACLES project which is supported by the European Commission Seventh Framework Programme under Grant Agreement No. 613588. | |
dc.language.iso | eng | es_ES |
dc.publisher | MDPI | es_ES |
dc.rights | Atribución-NoComercial-SinDerivadas 3.0 España | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/es/ | * |
dc.subject.other | Anti-inflammatory | es_ES |
dc.subject.other | Bioactive molecules | es_ES |
dc.subject.other | Microalgae | es_ES |
dc.subject.other | Polysaccharides | es_ES |
dc.subject.other | Carotenoids | es_ES |
dc.subject.other | Polyunsaturated fatty acids | es_ES |
dc.title | Chemically-Induced Production of Anti-Inflammatory Molecules in Microalgae | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.identifier.doi | 10.3390/md16120478 | |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es_ES |