Thesis Collection
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Browsing by Author "Abril, Nieves"
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Functional genomics and metabolomics reveal the toxicological effects of cadmium in Mus musculus mice
García Sevillano, Miguel Ángel
; Abril, Nieves; Fernández Cisnal, R.; García Barrera, Tamara; Pueyo, Carmen; López Barea, Juan; Gómez Ariza, José Luis (Springer Verlag, 2015)
Cadmium (Cd) is an environmental pollutant that accumulates in the organisms causing serious health problems. Over the past decades, omics studies have been conducted trying to elucidate changes in the genome, the transcriptome ... -
Impact of “chemical cocktails” exposure in shaping mice gut microbiota and the role of selenium supplementation combining metallomics, metabolomics, and metataxonomics
Arias Borrego, Ana; Selma Royo, Marta; Collado, Maria Carmen; Abril, Nieves; García Barrera, Tamara (Elsevier, 2022-06-20)
Biological systems are exposed to a complex environment in which pollutants can interact through synergistic or antagonistic mechanisms, but limited information is available on the combined effects. To this end, ... -
Metabolic impairments caused by a “chemical cocktail” of DDE and selenium in mice using direct infusion triple quadrupole time of flight and gas chromatography mass spectrometry
Rodríguez Moro, Gema; Abril, Nieves; Jara Biedma, Rocío; Ramírez Acosta, Sara; Gómez Ariza, José Luis; García Barrera, Tamara (2019-09-12)
Among organic contaminants, pesticides are one of the most important groups of chemicals due to their persistent character and toxicity. However, the biological systems are exposed to a complex environment in which the ... -
Mice brain metabolomics after the exposure to a “chemical cocktail” and selenium supplementation through the gut-brain axis
Parra Martínez, Cecilio; Selma Royo, Marta; Callejón Leblic, María Belén; Collado, Maria Carmen; Abril, Nieves; García Barrera, Tamara (Elsevier, 2022-09-15)
Several environmental pollutants have been shown to damage brain and affect gut microbiota. Limited evidence is available about the impact of “chemical cocktails” (CC) of xenobiotics on brain metabolome and their possible ... -
Omics technologies and their applications to evaluate metal toxicity in mice M. spretus as a bioindicator
García Sevillano, Miguel Ángel; García Barrera, Tamara; Abril, Nieves; Pueyo, Carmen; López Barea, Juan; Gómez Ariza, José Luis (Elsevier, 2014)
Metals are important components of living organisms since many biological functions critically depend on their interaction with some meta l in the cell. However, human activities have increased toxic metal levels in the ... -
Targeted and untargeted metabolomic analysis of Procambarus clarkii exposed to a “chemical cocktail” of heavy metals and diclofenac
Rodríguez Moro, Gema; Román Hidalgo, Cristina; Ramírez Acosta, Sara; Aranda Merino, Noemí; Gómez Ariza, José Luis; Abril, Nieves; Bello López, Miguel Ángel; Fernández Torres, Rut; García Barrera, Tamara (Elsevier, 2021)
Water pollution poses an important problem, but limited information is available about the joined effects of xenobiotics of different chemical groups to evaluate the real biological response. Procambarus clarkii (P. clarkii) ... -
Untargeted Gut Metabolomics to Delve the Interplay between Selenium Supplementation and Gut Microbiota
Callejón Leblic, María Belén; García Barrera, Tamara; Gómez Ariza, José Luis; Abril, Nieves; Selma Royo, Marta; Collado, Maria Carmen (American Chemical Society, 2021)
Selenium (Se) is an essential trace element with important health roles due to the antioxidant properties of selenoproteins. To analyze the interplay between Se and gut microbiota, gut metabolomic profiles were determined ...
